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DTSTART;TZID=Europe/London:20220509T193000
DTEND;TZID=Europe/London:20220509T213000
DTSTAMP:20260411T090613
CREATED:20220407T133529Z
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SUMMARY:Not All Genes are Equal (Pint of Science)
DESCRIPTION:Every person has two copies of each gene\, one inherited from each parent. Most genes are the same in all people\, but a small number of them are slightly different. These tiny differences contribute to each person’s unique physical features.\nLet’s explore rare imprinted genes\, a special class where one parental copy is switched off\,  and the life long impact that can have\, and consider what happens when your genes make you slightly more hungry all of the time. \n  \nIs obesity a choice? Led by Dr Giles Yeo\nIt is clear that the cause of obesity is a result of eating more than you burn. It is physics. What is more complex to answer is why some people eat more than others? Differences in our genetic make-up mean some of us are slightly more hungry all the time and so eat more than others. In contrast to the prevailing view\, obesity is not a choice. People with obesity are not bad or lazy; rather\, they are fighting their biology. \nA genetic battle of the sexes and rare imprinting disorders.  Led by Dr Miguel Constância\nImprinted genes are a special class of genes because one of the two parental copies is silenced by epigenetic mechanisms during development. These genes have key roles in how we acquire resources in the womb and throughout life.\nUnlike genetic changes\, epigenetic changes are reversible and do not change your DNA sequence\, but they can change how your body reads a DNA sequence.\nIn this talk we’ll explore what happens when the only active copy of imprinted genes is deleted\, mutated or silenced due to epigenetics and what happens if the silent copy of imprinted genes becomes activated.
URL:https://www.m4rd.org/event/not-all-genes-are-equal-pint-of-science/
LOCATION:Espresso Library\, 210 East Road\, Cambridge\, Cambridgeshire\, CB1 1BG\, United Kingdom
CATEGORIES:Festival
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ORGANIZER;CN="CRDN":MAILTO:jo@camraredisease.org
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DTSTART;TZID=Europe/London:20220510T193000
DTEND;TZID=Europe/London:20220510T213000
DTSTAMP:20260411T090613
CREATED:20220407T134132Z
LAST-MODIFIED:20220407T134132Z
UID:9265-1652211000-1652218200@www.m4rd.org
SUMMARY:Curing with Kindness: Rare Childhood Brain Tumours (Pint of Science)
DESCRIPTION:Researchers developing new treatments for children with rare brain tumours know that it’s not a case of treating children like tiny adults and that surviving the disease isn’t enough.\nReducing the damage done by treatments is just as important to the survivor. Discover how researchers are minimising damage and why they think studying rare children’s tumours is vital to our wider understanding. \n  \nAre rare tumours worth studying? with Sigourney Bell\nWhy is it important that we study paediatric tumours and how are they different to adult cancers? What does the future look like for rare paediatric brain tumours and how can we work towards a better future for these children? \nCuring with Kindness – New therapies for curable rare brain tumours with Dr Jessica Taylor\nI work at CRUK Cambridge Institute finding new therapies for children with a rare\, yet curable brain tumour. However\, a cure isn’t enough for these children. After surgery\, radiation and aggressive chemotherapy mean that they suffer from a multitude of different side-effects\, both short-term and long lasting. We aim to find cures that focus not only on surviving cancer\, but on the survivor.
URL:https://www.m4rd.org/event/curing-with-kindness-rare-childhood-brain-tumours-pint-of-science/
LOCATION:Espresso Library\, 210 East Road\, Cambridge\, Cambridgeshire\, CB1 1BG\, United Kingdom
CATEGORIES:Festival
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ORGANIZER;CN="CRDN":MAILTO:jo@camraredisease.org
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